To understand periodontal disease, researchers examine the surprising behavior of T cells

In diseases characterized by bone loss -such as periodontitis, rheumatoid arthritis, and osteoporosis- there is a lot that scientists still don’t understand. What is the role of the immune response in the process? What happens to the regulatory mechanisms that protect bone? In a paper published recently in Scientific Reports, researchers from the Forsyth Institute […]

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Early warning system fills in gaps in infectious disease surveillance

Researchers at Columbia University Mailman School of Public Health developed an infectious disease early warning system that includes areas lacking health clinics participating in infectious disease surveillance. The approach compensates for existing gaps by optimally assigning surveillance sites that support better observation and prediction of the spread of an outbreak, including to areas remaining without […]

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Youth with family history of suicide attempts have worse neurocognitive functioning

Children and adolescents with a family history of suicide attempts have lower executive functioning, shorter attention spans, and poorer language reasoning than those without a family history, according to a new study by researchers from the Lifespan Brain Institute (LiBI) of Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania. The study is the […]

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Big data analysis finds cancer’s key vulnerabilities

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer’s origin, tumors could be stratified in only 112 subtypes and that, within each subtype, the Master Regulator proteins that control the cancer’s transcriptional state were virtually identical, independent of the specific […]

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